Trimipramine-D3 Maleate is a tricyclic antidepressant (TCA) which is used to treat depression. Trimipramine’s primary use in medicine is in the treatment of major depressive disorder, especially where sedation is helpful due to its prominent sedative effects. The drug is also an effective anxiolytic, and can be used in the treatment of anxiety. The drug is described as an atypical or “second-generation” TCA because, unlike other TCAs, it seems to be a fairly weak monoamine reuptake inhibitor.
Trimipramine-D3 Maleate – Surmontil – CAS 1185245-93-5
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Description
Trimipramine-D3 Maleate
| Product reference number | TRP-1877-MA |
| Full chemical name | 3-(5,6-Dihydrobenzo[b][1]benzazepin-11-yl)-N-trideuteromethyl,N,2-dimethylpropan-1-amine.cis-butendioic acid |
| Formula | C20H23D3N2⋅C4H4O4 |
| Molecular weight | 413.53 |
| CAS Number | 1185245-93-5 |
| Supplied as | maleate salt |
| Appearance | white to off-white crystalline powder |
| IR | IR corresponds |
| NMR | corresponds to structure |
| MS | MH+ corresponds |
| UV max [nm] (mol, solvent) | 210.0 ± 1.0 (43000 ± 4000, methanol); 250.0 ± 1.0 (10000 ± 1000, methanol) |
| Melting point [Celsius] | 142 ±3 |
| HPLC purity [%] | > 98.5 |
| Free base content [%] | > 69.9 |
| Water content [%] | < 1 |
| Isotopic enrichment [%] | D0/D3 < 1 |
| Calculated maleate content [%] | 28.1 |
Trimipramine-D3 Maleate is a tricyclic antidepressant (TCA) which is used to treat depression. it seems to be a fairly weak monoamine reuptake inhibitor. Trimipramine’s primary use in medicine is in the treatment of major depressive disorder.
Antidepressants, Surmontil, Rhotrimine, Stangyl, CAS 1185245-93-5, Trimeproprimine, IF-6120, IL-6001, RP-7162, 2′-Methylimipramine, β-Methylimipramine
