Triazolam – Halcion – CAS 28911-01-5

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Triazolam – Halcion – CAS 28911-01-5

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Triazolam is usually used for short-term treatment of acute insomnia and circadian rhythm sleep disorders, including jet lag. It is sold under the brand name Halcion among others, is a central nervous system (CNS) depressant tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepine (BZD) derivatives. This product is designed for qualitative and quantitative protocols and can be used for forensic, toxicology, research, and other chemical/biochemical analytical applications.

Description

Triazolam

Product reference number TRI-1832-HC
Full chemical name 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Formula C17H12Cl2N4
Molecular weight 343.21 g·mol−1
CAS Number 28911-01-5
Supplied as hydrochloride salt
Appearance white to off-white crystalline powder
IR IR corresponds
NMR corresponds to structure
MS MH+ corresponds
UV max [nm] (mol, solvent) 210.0 ± 1.0 (17000 ± 1700, methanol);
238.0 ± 1.0 (25000 ± 2500, methanol);
300.0 ± 1.0 (2500 ± 250, methanol)
Melting point [Celsius] 190 ± 3
HPLC purity [%] > 98.5
Free base content [%] > 89.0
Water content [%] < 1
Calculated hydrochloride content [%] 8.6

Triazolam (Halcion) is a rapid onset, short duration of action, and lack of active metabolites also make it a nearly ideal antianxiety medication for dental outpatients. Triazolam is chemically related to diazepam and is indicated for the treatment of insomnia.

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