Norfentanyl – CAS 1609-66-1

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Norfentanyl – CAS 1609-66-1


Norfentanyl is an analog and metabolite of fentanyl with the removal of the phenethyl moiety (or functional group) from fentanyl chemical structure. Norfentanyl occurs primarily as a metabolite of its parent drug, fentanyl. However, it can also be used to synthesize fentanyl itself. It is an inactive synthetic opioid analgesic drug precursor.



Product reference number NOR-1608-OP
Full chemical name N-phenyl-N-(piperidin-4-yl)propionamide
Formula C14H20N2O
Molecular weight 232.327 g·mol−1
CAS Number 1609-66-1
Appearance white to off-white crystalline powder
IR IR corresponds
NMR corresponds to structure
MS MH+ corresponds
UV max [nm] (mol, solvent) 229.0 ± 1.0 nm (11000 ± 1000, methanol)
Melting point [Celsius] 70 ± 3
HPLC purity [%]  > 98.5
Water content [%] < 1
Isotopic enrichement [%] D0/D5 < 1

Norfentanyl is a monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of 4-(N’ phenyl)piperidin-4-amine with propanoic acid. It has a role as an opioid analgesic and a drug metabolite. A major metabolite of fentanyl. Norfentanyl is an anilide, a member of piperidines and a monocarboxylic acid amide.

Norfentanil, N-phenyl-N-(piperidin-4-yl)propionamide, Propanamide, N-phenyl-N-4-piperidinyl-, N-Phenyl-N-piperidin-4-yl-propionamide, CAS 1609-66-1, Norfentanyl monohydrate, 4-(N-propionylanilino)piperidine, Fentanyl-M nor, Synthetic opioid analgesic, Fentanyl Precursor


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