Isotonitazene – Nitazene Powder – CAS 14188-81-9

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Isotonitazene – Nitazene Powder – CAS 14188-81-9


Isotonitazene is a benzimidazole derived opioid analgesic drug related to etonitazene. It has only around half the potency of etonitazene in animal studies, but it is likely even less potent in humans as was seen with etonitazene (1000 times as potent as morphine in animal models yet only 60 times as potent in humans). Isotonitazene been sold as a designer drug, and can be obtained from an online vendor. Side effects of benzimidazole derived opioids are likely to be similar to those of fentanyl, which include itchingnausea and potentially serious respiratory depression, which can be life-threatening.



Product reference number ISO-1638-FB
Full chemical name N,N-Diethyl-2-(2-((4-isopropoxyphenyl)methyl)-5-nitro-benzimidazol-1-yl)ethanamine
Molecular weight 410.5
DEA No. 9740 CII
Appearance white to off-white crystalline powder
IR IR corresponds
NMR corresponds to structure
MS MH+ corresponds
UV max [nm] (mol, solvent) 229.0 ± 1.0 nm (11000 ± 1000, methanol)
Melting point [Celsius] 70 ± 3
HPLC purity [%]  > 98.5
Water content [%] < 1
Isotopic enrichement [%] D0/D5 < 1

Isotonitazene (Nitazene or “ISO”) is a particular synthetic opioid. It is much more potent than heroin and morphine (similar to fentanyl). In powder form, Isotonitazane can appear yellow, brown, or off-white in color. This product is intended for research and forensic applications.

Benzimidazole, CAS 14188-81-9, Etonitazene, Fentanyl Analog, ISO (OPIOID RECEPTOR AGONIST), ISO Powder, New Synthetic Opioid, Nitazene, TONI, Tony Powder, Isotonitazene



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