Isotonitazene is a benzimidazole derived opioid analgesic drug related to etonitazene. It has only around half the potency of etonitazene in animal studies, but it is likely even less potent in humans as was seen with etonitazene (1000 times as potent as morphine in animal models yet only 60 times as potent in humans). Isotonitazene been sold as a designer drug, and can be obtained from an online vendor. Side effects of benzimidazole derived opioids are likely to be similar to those of fentanyl, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.
Isotonitazene – Nitazene Powder – CAS 14188-81-9
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Description
Isotonitazene
| Product reference number | ISO-1638-FB | |
| Full chemical name | N,N-Diethyl-2-(2-((4-isopropoxyphenyl)methyl)-5-nitro-benzimidazol-1-yl)ethanamine | |
| Formula |
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| Molecular weight | 410.5 | |
| DEA No. | 9740 CII | |
| Appearance | white to off-white crystalline powder | |
| IR | IR corresponds | |
| NMR | corresponds to structure | |
| MS | MH+ corresponds | |
| UV max [nm] (mol, solvent) | 229.0 ± 1.0 nm (11000 ± 1000, methanol) | |
| Melting point [Celsius] | 70 ± 3 | |
| HPLC purity [%] | > 98.5 | |
| Water content [%] | < 1 | |
| Isotopic enrichement [%] | D0/D5 < 1 |
Isotonitazene (Nitazene or “ISO”) is a particular synthetic opioid. It is much more potent than heroin and morphine (similar to fentanyl). In powder form, Isotonitazane can appear yellow, brown, or off-white in color. This product is intended for research and forensic applications.
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