Bromazolam – XLI-268 – CAS 71368-80-4

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Bromazolam – XLI-268 – CAS 71368-80-4

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Bromazolam is structurally similar to alprazolam but is the bromo rather than the chloro analog. It is a Triazolobenzodiazepine that is known as research chemical XLI-268. Bromazolam is a non subtype selective agonist at the benzodiazepine site of GABAA receptors, with a binding affinity of 2.81nM at the α1 subtype, 0.69nM at α2 and 0.62nM at α5.
This product is designed for use in qualitative and quantitative protocols and can be used for forensic, toxicology, research, and other chemical/biochemical analytical applications.

Description

Bromazolam

Product reference number  BUT-1637-FA
Full chemical name 8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Formula C17H13BrN4
Molecular weight 353.223 g·mol−1
CAS Number 71368-80-4
DEA No. 2100 CIII
Appearance white to off-white crystalline powder
IR IR corresponds
NMR corresponds to structure
MS MH+ corresponds
UV max [nm] (mol, solvent) 244.0 ± 1.0 (5500 ± 500, 0.1 N NaOH)
Melting point [Celsius] 139 ± 3
HPLC purity [%] > 98.5
Water content [%] < 1
Isotopic enrichment [%] D0/D5 < 1

Bromazolam is a non-subtype selective agonist at the benzodiazepine site of GABAA receptors, withbinding affinity of 2.81nM at the α1 subtype, 0.69nM at α2 and 0.62nM at α5.[5]

Benzodiazepines, CAS 71368-80-4, DE(chloro)-bromo-alprazolam, Sedatives/Hypnotics, TBZD, Triazolobenzodiazepine, XLI-268

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